On Behalf of the Nephrology & Transplantation Unit Staff Members, Faculty of Medicine, Alexandria University, it is our great pleasure to welcome you to NephroAlex 2025. Building upon years of successful collaboration, we are delighted to present our recognized scientific conference, continuing our commitment to advancing knowledge in nephrology. This year, under the theme "CKD: from screening to ESKD," we will place a strong emphasis on interactive activities, fostering effective communication and practical solutions for the challenges we face daily. We believe that progress in nephrology hinges on this dynamic exchange of ideas. Beyond updates across the spectrum of CKD – from the Cardio-Kidney-Metabolic Syndrome and the impact of obesity, to conservative and symptom management, and preparing for RRT – NephroAlex 2025 will provide a platform for in-depth discussion and the application of established guidelines. Your esteemed presence and active participation are invaluable to us, and we eagerly anticipate a stimulating and productive conference at the Golden Jewel Hotel this July 31st and August 1st.